optiQGain introduces an affordable, real-time, lightweight & on-site system for high resolution molecular level analysis

The proposed unique solution is based on an innovative, general purpose SRS
(Stimulated Raman Scattering) spectrophotometer module, capable of generating a high resolution Raman spectrum in 0.1 second. The device directly illuminates samples with laser beams and by analyzing the emitted laser radiation provides real-time detection and concentration of intended target molecules; the system supports sampling multiple targets simultaneously.

Areas Of Activities


Production Control


The Technology

Technology Background

Stimulated Raman Scattering (SRS) Spectroscopy – based on the Raman phenomenon. Most metabolites possess a unique “Raman-fingerprint” which can be used for their specific, accurate detection and concentration measurements. Spontaneous Raman detection is used in the industry for over 20 years (hampered by long acquisition time and low sensitivity). In SRS, two laser beams illuminate a sample providing amplification at the vibrational transition rate, increasing the Raman signal by several orders of magnitude.
For more information on SRS and SRS capabilities, see publication by X. Sunney Xie (Harvard University) in Science journal vol. 322 Dec. 2008

Technology Breakthrough

Low cost SRS Spectrophotometer: due to large size and very high manufacturing costs, SRS is currently used in academics and has not yet been implemented in the industry. optiQGain introduces an innovative, small size, low cost SRS spectrophotometer (patent pending) while maintaining high resolution performances. This is achieved by a totally new approach to the SRS implementation – a design of a system based on re-configuration of off-the-shelf electro-optic components, while compensating for components impairments by applying DSP algorithms to the received signals.
Combining SRS module with a pre-concentration & separation unit – enables detection of trace quantities (nano & pico grams) and provides a key tool for on-line direct analysis in medical, food & beverage and environmental industries


optiQGain Ltd. was founded in late 2011 by experienced multidisciplinary Israeli entrepreneurs, with a proven track record in R&D and in bringing products to mass market. optiQGain is currently funded and in strategic partnership with leading energy manufactures and has been awarded two lucrative multinational grants to facilitate research and development

This project has received funding from the European Union Horizon 2020 research and innovation programme under grant agreement No. 859111.